Phylogenetic methods come of age: Testing hypotheses in an evolutionary context

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Publicat a:Science vol. 276, no. 5310 (Apr 11, 1997), p. 227-232
Autor principal: Huelsenbeck, John P
Altres autors: Rannala, Bruce
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The American Association for the Advancement of Science
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100 1 |a Huelsenbeck, John P 
245 1 |a Phylogenetic methods come of age: Testing hypotheses in an evolutionary context 
260 |b The American Association for the Advancement of Science  |c Apr 11, 1997 
513 |a Feature 
520 3 |a The use of molecular phylogenies to examine evolutionary questions has become commonplace with the automation of DNA sequencing and the availability of efficient computer programs to perform phylogenetic analyses. The application of computer simulation and likelihood ratio tests to evolutionary hypotheses represents a recent methodological development in this field. Likelihood ratio tests have enabled biologists to address many questions in evolutionary biology that have been difficult to resolve in the past, such as whether host-parasite systems are cospeciating and whether models of DNA substitution adequately explain observed sequences. 
650 2 2 |a Evolution 
650 2 2 |a Evolution, Molecular 
650 2 2 |a Phylogeny 
653 |a Molecules 
653 |a Simulation 
653 |a Biology 
653 |a Biologists 
653 |a Parasites 
653 |a Deoxyribonucleic acid--DNA 
653 |a Computer Simulation 
653 |a Mathematical Models 
653 |a Communicable Diseases 
653 |a Probability 
653 |a Topology 
653 |a Hypothesis Testing 
653 |a Monte Carlo Methods 
653 |a Maximum Likelihood Statistics 
653 |a Environmental 
700 1 |a Rannala, Bruce 
773 0 |t Science  |g vol. 276, no. 5310 (Apr 11, 1997), p. 227-232 
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