Rapid polygenic adaptation in a wild population of ash trees under a novel fungal epidemic

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Dades bibliogràfiques
Publicat a:	bioRxiv (Jan 13, 2025)
Autor principal:	Carey Louise Metheringham
Altres autors:	Plumb, William, Flynn, William, Stocks, Jonathan, Kelly, Laura, Miguel Nemesio Gorriz, Grieve, Stuart, Moat, Justin, Lines, Emily, Buggs, Richard, Nichols, Richard A
Publicat:	Cold Spring Harbor Laboratory Press
Matèries:	Breeding Trees Pathogens Natural selection Population genetics Gene frequency Dieback Alleles Single-nucleotide polymorphism Genomics Epidemics Genetic diversity Fraxinus excelsior
Accés en línia:	Citation/Abstract Full text outside of ProQuest
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Descripció
Resum:	Rapid evolution via small shifts in allele frequencies at thousands of loci are a long-standing neo-Darwinian prediction but are hard to characterize in the wild. European ash tree (Fraxinus excelsior) populations have recently come under strong selection by the invasive fungal pathogen Hymenoscyphus fraxineus. Using genomic prediction models based on field trial phenotypes and 7,985 loci, we show a shift in genomically estimated breeding values in an ancient woodland, between adult trees established before the epidemic started and juvenile trees established since. Using simulations, we estimate that natural selection has eliminated 31% of the juvenile population. Thus, we document a highly polygenic heritable micro-evolutionary adaptive change over a single generation in the wild.Competing Interest StatementThe authors have declared no competing interest.Footnotes* Added new analyses and UAV data* https://www.ebi.ac.uk/ena/browser/view/PRJEB44697* https://github.com/CareyMetheringham/MardenPark* https://doi.org/10.5281/zenodo.10808942
ISSN:	2692-8205
DOI:	10.1101/2022.08.01.502033
Font:	Biological Science Database