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Metabolomic profiling reveals grade-specific niacinamide accumulation and its therapeutic Potential via SIRT1-CD38-EMT axis modulation in cervical cancer progression

Furkejuvvon:
Publikašuvnnas:bioRxiv (Dec 20, 2024)
Váldodahkki: Jaiswal, Shivani
Eará dahkkit: Mishra, Vivek, Majumder, Srija, Wangikar, Pramod P, Sengupta, Shinjinee
Almmustuhtton:
Cold Spring Harbor Laboratory Press
Fáttát:
Liquid chromatography
Precision medicine
Cervical carcinoma
Amino acid sequence
Drug resistance
Cell proliferation
Toxicity
Molecular modelling
Phosphatidylcholine
Metabolism
Transcriptomics
Chromatography
Genotypes
Human papillomavirus
Metabolic response
CD38 antigen
Medical innovations
Ionization
Cervical cancer
Apoptosis
Glycolysis
Nicotinamide
Tumor cell lines
Mass spectroscopy
Citric acid
Gene expression
Lecithin
Tricarboxylic acid cycle
Metabolites
Liŋkkat:Citation/Abstract
Full text outside of ProQuest
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