Toxidromes and a general approach to poisoning

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Publicado en:Archives of Disease in Childhood (Feb 2025), p. archdischild-2024-326969
Autor principal: Hoffman, Robert J
Otros Autores: Nillas, Andrea
Publicado:
BMJ Publishing Group LTD
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Acceso en línea:Citation/Abstract
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100 1 |a Hoffman, Robert J  |u Pediatrics, Emergency Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA 
245 1 |a Toxidromes and a general approach to poisoning 
260 |b BMJ Publishing Group LTD  |c Feb 2025 
513 |a Journal Article 
520 3 |a A toxicologic syndrome, or toxidrome, is a distinct pattern of effects of poisoning. Well-defined toxidromes are the opioid, anticholinergic, cholinergic and sympathomimetic, and an additional described toxidrome is GABAergic. These toxidromes are named for the receptor effects causing their specific clinical findings, and knowledge of toxidromes allows rapid pattern recognition of specific poisonings. In this review, toxidromes and the initial assessment and general approach to management of acute poisoning are discussed. This article details the receptor-level effects of the poisoning, key clinical signs and symptoms and the role antidotes play in treatment. Clinical resources such as Toxbase and others exist to provide detailed guidance on clinical management of poisoning. 
651 4 |a United Kingdom--UK 
653 |a Urinary retention 
653 |a Drug withdrawal 
653 |a Anticholinergics 
653 |a Delirium 
653 |a Toxicology 
653 |a Urination 
653 |a Pattern recognition 
653 |a Fatalities 
653 |a Poisoning 
653 |a Dopamine 
653 |a Blood pressure 
653 |a Enzymes 
653 |a Benzodiazepines 
653 |a Heart rate 
653 |a Convulsions & seizures 
653 |a Toxicity 
653 |a γ-Aminobutyric acid 
653 |a Vital signs 
653 |a Antidotes 
653 |a Poisons 
653 |a Patients 
653 |a Coma 
653 |a Cardiac arrhythmia 
653 |a Hypertension 
653 |a Psychosis 
653 |a Adrenergic receptors 
653 |a Opioid receptors 
653 |a Nervous system 
653 |a Toxins 
653 |a Pediatrics 
653 |a Literature Reviews 
653 |a Narcotics 
653 |a Anatomy 
653 |a Medical Evaluation 
653 |a Mnemonics 
653 |a Cocaine 
653 |a Physical Examinations 
653 |a Database Management Systems 
653 |a Visual Impairments 
653 |a Depression (Psychology) 
653 |a Social 
653 |a Meta Analysis 
700 1 |a Nillas, Andrea  |u Emergency Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA 
773 0 |t Archives of Disease in Childhood  |g (Feb 2025), p. archdischild-2024-326969 
786 0 |d ProQuest  |t Science Database 
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