Production of an Innovative, Surface Area‐Enhanced and Biodegradable Biofilm‐Generating Device by 3D Printing

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Udgivet i:Engineering in Life Sciences vol. 25, no. 2 (Feb 1, 2025)
Hovedforfatter: Datta, Atulona
Andre forfattere: Saha, Rituparna, Sahoo, Sovan, Roy, Arup Ratan, Basu, Shayontani, Mahajan, Girish, Panja, Subhash Chandra, Mukherjee, Joydeep
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John Wiley & Sons, Inc.
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LEADER 00000nab a2200000uu 4500
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022 |a 1618-2863 
024 7 |a 10.1002/elsc.202400046  |2 doi 
035 |a 3171800741 
045 0 |b d20250201 
100 1 |a Datta, Atulona  |u School of Environmental Studies, Jadavpur University, Kolkata, India 
245 1 |a Production of an Innovative, Surface Area‐Enhanced and Biodegradable Biofilm‐Generating Device by 3D Printing 
260 |b John Wiley & Sons, Inc.  |c Feb 1, 2025 
513 |a Journal Article 
520 3 |a ABSTRACT The enhanced surface cylindrical flask (ESCF) consists of an eight‐striped inner arrangement holding 16 standard microscopic slides placed inside a cylindrical vessel. The specially designed spatula‐accessible slides can be withdrawn from the vessel during cultivation without disturbing biofilm formation through an innovative window‐flap accessibility mechanism. The vessel and its accessories were three‐dimensional (3D) printed by applying a fused deposition modeling technique utilizing biodegradable polylactic acid. Biofilms of clinically relevant bacteria namely Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli were successfully grown in the ESCF and observed through confocal laser scanning microscopy. Advantages of the device include an enhanced surface area for biofilm formation, ease of insertion and removal of microscopic slides, convenient fitting into standard rotary shaker platforms, creation of anoxic/microaerophilic environment inside the vessel as well as the feasibility of pH, dissolved gases, and metabolite measurements in the liquid surrounding the biofilm. The ESCF will find widespread application in medical, industrial, and environmental disciplines. 
610 4 |a Jadavpur University 
651 4 |a India 
653 |a Software 
653 |a Fused deposition modeling 
653 |a Accessibility 
653 |a Transplants & implants 
653 |a Klebsiella 
653 |a pH 
653 |a Surface area 
653 |a Biofilms 
653 |a Water treatment 
653 |a Scanning microscopy 
653 |a Design specifications 
653 |a Confocal microscopy 
653 |a Metabolites 
653 |a Biodegradability 
653 |a Polylactic acid 
653 |a Three dimensional printing 
653 |a Visualization 
653 |a Polymers 
653 |a Dissolved gases 
653 |a Computer aided design--CAD 
653 |a Medical research 
653 |a 3-D printers 
653 |a E coli 
653 |a Shipping industry 
700 1 |a Saha, Rituparna  |u Department of Mechanical Engineering, Jadavpur University, Kolkata, India 
700 1 |a Sahoo, Sovan  |u Department of Mechanical Engineering, Jadavpur University, Kolkata, India 
700 1 |a Roy, Arup Ratan  |u School of Environmental Studies, Jadavpur University, Kolkata, India 
700 1 |a Basu, Shayontani  |u School of Environmental Studies, Jadavpur University, Kolkata, India 
700 1 |a Mahajan, Girish  |u HiMedia Laboratories Pvt. Ltd., Thane (West), India 
700 1 |a Panja, Subhash Chandra  |u Department of Mechanical Engineering, Jadavpur University, Kolkata, India 
700 1 |a Mukherjee, Joydeep  |u School of Environmental Studies, Jadavpur University, Kolkata, India 
773 0 |t Engineering in Life Sciences  |g vol. 25, no. 2 (Feb 1, 2025) 
786 0 |d ProQuest  |t Engineering Database 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3171800741/abstract/embedded/L8HZQI7Z43R0LA5T?source=fedsrch 
856 4 0 |3 Full Text  |u https://www.proquest.com/docview/3171800741/fulltext/embedded/L8HZQI7Z43R0LA5T?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3171800741/fulltextPDF/embedded/L8HZQI7Z43R0LA5T?source=fedsrch