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Case report: Coexistence of rectal signet ring cell carcinoma with neuroendocrine components

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Publicado no:BMC Geriatrics vol. 25 (2025), p. 1
Autor principal: Xu, Ling
Outros Autores: He, Zhefeng, Fu, Chao, Wu, Yiyang, Wu, Anwei, Tian, Guojiang, Huang, Jianfei, Liu, Xibo, Wang, Qi
Publicado em:
Springer Nature B.V.
Assuntos:
Histopathology
Metastasis
Biopsy
Cancer therapies
Intestinal obstruction
Laparoscopy
Adenocarcinoma
Cell differentiation
Colorectal cancer
Blood
Carcinoma
Patients
Cells
Medical prognosis
Colonoscopy
Lymphatic system
Hospitals
Rectum
Colorectal carcinoma
Antigens
Defecation
Tumors
Lymphoma
Chemotherapy
Endoscopy
Case reports
Acesso em linha:Citation/Abstract
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Resumo:BackgroundSignet ring cell carcinoma is a rare histological type among the various forms of colorectal cancers. Even rare is when it coexisted with neuroendocrine components in one tumor. To date, there is little literature reported case of colorectal cancer diagnosed as signet ring cell carcinoma with neuroendocrine components.Case presentationThis report presents a unique case manifested as obstructed defecation for more than one month but with negative endoscopic biopsies. Laparoscopic abdominoperineal resection was performed. Based on the postoperative pathology, the patient was finally diagnosed as signet ring cell carcinoma with neuroendocrine differentiation among poorly differentiated adenocarcinoma.Discussion and conclusionsWe highlight the rare coexistence of signet ring cell carcinoma and neuroendocrine differentiation in this case. We also emphasize the special characteristic of intramural growth without penetrating the mucosa in signet ring cell carcinoma, further to pose the pitfalls and share lessons during our diagnosis and treatment process.
ISSN:1471-2318
DOI:10.1186/s12877-025-06037-x
Fonte:Health & Medical Collection