Case report: Coexistence of rectal signet ring cell carcinoma with neuroendocrine components

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Publicado en:BMC Geriatrics vol. 25 (2025), p. 1
Autor principal: Xu, Ling
Otros Autores: He, Zhefeng, Fu, Chao, Wu, Yiyang, Wu, Anwei, Tian, Guojiang, Huang, Jianfei, Liu, Xibo, Wang, Qi
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Springer Nature B.V.
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Acceso en línea:Citation/Abstract
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022 |a 1471-2318 
024 7 |a 10.1186/s12877-025-06037-x  |2 doi 
035 |a 3216558663 
045 2 |b d20250101  |b d20251231 
084 |a 58497  |2 nlm 
100 1 |a Xu, Ling 
245 1 |a Case report: Coexistence of rectal signet ring cell carcinoma with neuroendocrine components 
260 |b Springer Nature B.V.  |c 2025 
513 |a Journal Article Case Study 
520 3 |a BackgroundSignet ring cell carcinoma is a rare histological type among the various forms of colorectal cancers. Even rare is when it coexisted with neuroendocrine components in one tumor. To date, there is little literature reported case of colorectal cancer diagnosed as signet ring cell carcinoma with neuroendocrine components.Case presentationThis report presents a unique case manifested as obstructed defecation for more than one month but with negative endoscopic biopsies. Laparoscopic abdominoperineal resection was performed. Based on the postoperative pathology, the patient was finally diagnosed as signet ring cell carcinoma with neuroendocrine differentiation among poorly differentiated adenocarcinoma.Discussion and conclusionsWe highlight the rare coexistence of signet ring cell carcinoma and neuroendocrine differentiation in this case. We also emphasize the special characteristic of intramural growth without penetrating the mucosa in signet ring cell carcinoma, further to pose the pitfalls and share lessons during our diagnosis and treatment process. 
653 |a Histopathology 
653 |a Metastasis 
653 |a Biopsy 
653 |a Cancer therapies 
653 |a Intestinal obstruction 
653 |a Laparoscopy 
653 |a Adenocarcinoma 
653 |a Cell differentiation 
653 |a Colorectal cancer 
653 |a Blood 
653 |a Carcinoma 
653 |a Patients 
653 |a Cells 
653 |a Medical prognosis 
653 |a Colonoscopy 
653 |a Lymphatic system 
653 |a Hospitals 
653 |a Rectum 
653 |a Colorectal carcinoma 
653 |a Antigens 
653 |a Defecation 
653 |a Tumors 
653 |a Lymphoma 
653 |a Chemotherapy 
653 |a Endoscopy 
653 |a Case reports 
700 1 |a He, Zhefeng 
700 1 |a Fu, Chao 
700 1 |a Wu, Yiyang 
700 1 |a Wu, Anwei 
700 1 |a Tian, Guojiang 
700 1 |a Huang, Jianfei 
700 1 |a Liu, Xibo 
700 1 |a Wang, Qi 
773 0 |t BMC Geriatrics  |g vol. 25 (2025), p. 1 
786 0 |d ProQuest  |t Health & Medical Collection 
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856 4 0 |3 Full Text  |u https://www.proquest.com/docview/3216558663/fulltext/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
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