Drug Discovery and Development
Guardado en:
| Publicado en: | Asian Journal of Research in Pharmaceutical Science vol. 15, no. 2 (Jun 2025) |
|---|---|
| Publicado: |
Athena Information Solutions Pvt. Ltd.
|
| Materias: | |
| Acceso en línea: | Citation/Abstract Full Text |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
MARC
| LEADER | 00000nab a2200000uu 4500 | ||
|---|---|---|---|
| 001 | 3227592787 | ||
| 003 | UK-CbPIL | ||
| 022 | |a 2231-5640 | ||
| 022 | |a 2231-5659 | ||
| 035 | |a 3227592787 | ||
| 045 | 2 | |b d20250601 |b d20250630 | |
| 245 | 1 | |a Drug Discovery and Development | |
| 260 | |b Athena Information Solutions Pvt. Ltd. |c Jun 2025 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a [...]prudent investments and measured risks at this eventually, a specific moment can raise the risk of success for a new Potential4,6. The different stages or phases of the drug development and discovery process are20-24 Drug Discovery Period25-31 * Initiate drug discovery program Combinatorial chemistry * Lead compound series identification * Additional compounds are made NCE’ s identified Drug Development and Registration Period32-35 * IND plan established and initiated * IND filed * Clinical studies initiated * NDA prepared and submitted * Drug launched into the market Drug Marketing and Line Expansion36-41 * Post-Marketing surveillance initiated * New clinical indications pursued * New dosage forms and formulations developed * Activities conducted to support marketing Drug Discovery and Development: Drug Discovery: New studies into a disease process that motivate scientists to create a new product to prevent or reverse the disease’s effects are the usual ways that researchers find new drugs42,44. * Numerous molecular compound tests to identify potential protective effects against a wide range of illnesses * Current therapies with unexpected side effects45–51 * New technologies, such as those that offer novel approaches to genetic material manipulation or the delivery of pharmaceuticals to particular bodily locations52–54. Drug Development: After discovering a compound that shows promise for development, scientists carry out tests in order to understand more about60–66: * Its distribution, metabolism, excretion, and absorption * Its possible advantages and modes of action * The ideal dosage and method of delivery * Adverse effects also known as toxicity * The ways in which it impacts different age groups (e.g., by gender, race, or ethnicity) differently * How it affects other medications and therapies * Its efficacy in comparison to comparable medications Preclinical Trials: ICH has established a basic guideline for the technical necessities of acceptable preclinical drug development. Prior to the start of a clinical trial, researchers review existing data about the drug to formulate research questions and objectives75. * Selection criteria for participants * Number of people take part of the study * Duration of study * Dose and route of administration of dosage form * Assessment of parameters * Data collection and analysis Phase 1: | |
| 653 | |a Clinical trials | ||
| 653 | |a Pharmacokinetics | ||
| 653 | |a Computer simulation | ||
| 653 | |a Software | ||
| 653 | |a Drug development | ||
| 653 | |a Marketing | ||
| 653 | |a Metabolism | ||
| 653 | |a Toxicity | ||
| 653 | |a Surveillance | ||
| 653 | |a Research & development--R&D | ||
| 653 | |a Metabolites | ||
| 653 | |a Drug dosages | ||
| 653 | |a Medical research | ||
| 773 | 0 | |t Asian Journal of Research in Pharmaceutical Science |g vol. 15, no. 2 (Jun 2025) | |
| 786 | 0 | |d ProQuest |t Health & Medical Collection | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/3227592787/abstract/embedded/L8HZQI7Z43R0LA5T?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text |u https://www.proquest.com/docview/3227592787/fulltext/embedded/L8HZQI7Z43R0LA5T?source=fedsrch |