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Topical dobesilate eye drops for ophthalmic primary pterygium

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Publicado en:BMJ Case Reports vol. 2012 (Sep 2025), p. bcr1220115449
Autor Principal: Cuevas, Pedro
Outros autores: Outeiriño, Luis A, Angulo, Javier, Giménez-Gallego, Guillermo
Publicado:
BMJ Publishing Group LTD
Materias:
Diabetes
Vascular endothelial growth factor
Neutrophils
Fibroblasts
Stem cells
Cornea
Angiogenesis
Cytokines
Acceso en liña:Citation/Abstract
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Resumo:Selective inhibition of fibroblast growth factor and vascular endothelial growth factor signalling pathways is effective in causing regression of pterygia. Prompt regression of fibrovascular mass and conjunctival angiogenesis was documented 2 weeks after topical administration of dobesilate eye drops twice daily. At 3-month follow-up, no recurrence was seen and no ocular irritation and burning were noted. The authors believe that this is the first known successful use of topical dobesilate in primary pterygium.
ISSN:1757-790X
DOI:10.1136/bcr.12.2011.5449
Fonte:Health & Medical Collection