Graph-based pangenomes and pan-phenome provide a cornerstone for eggplant biology and breeding

Збережено в:

Бібліографічні деталі
Опубліковано в::	Nature Communications vol. 16, no. 1 (2025), p. 9919-9939
Автор:	Gaccione, Luciana
Інші автори:	Toppino, Laura, Bolger, Marie, Schmidt, Maximilian, Tassone, Maria Rosaria, Sulli, Maria, Idahl, Emily, Alonso, David, Aprea, Giuseppe, Ferrante, Paola, Lefebvre, Véronique, Boyaci, Hatice Filiz, Schafleitner, Roland, Gattolin, Stefano, Finkers, Richard, Brouwer, Matthijs, Bovy, Arnaud, Prohens, Jaime, Portis, Ezio, Lanteri, Sergio, Rotino, Giuseppe Leonardo, Giuliano, Giovanni, Usadel, Björn, Barchi, Lorenzo
Опубліковано:	Nature Publishing Group
Предмети:	Disease resistance Genetic analysis Phylogenetics Evolution Flowers & plants Plant breeding Domestication Biosynthesis Metabolomics Chromosomes Trees Assemblies Genomes Genetic diversity Genes Association analysis Fusarium oxysporum Solanum melongena Environmental
Онлайн доступ:	Citation/Abstract Full Text Full Text - PDF
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!

Опис
Короткий огляд:	Eggplant (Solanum melongena L.) is a major Solanaceous crop of Asian origin, but genomic resources remain limited compared to related species. Here, a core collection of 368 accessions spanning global diversity of S. melongena and wild relatives is phenotyped for agronomic, disease resistance and fruit metabolomic traits and resequenced. Additionally, 40 chromosome-level assemblies of S. melongena, its progenitor S. insanum and the allied species S. incanum enable the construction of two graph-based pangenomes, capturing broad genetic variation. We demonstrate the power of these datasets by identifying major loci controlling prickliness and resistance to Fusarium oxysporum f. sp. melongenae, driven by SVs affecting the LONELY GUY 3 gene and a resistance gene cluster, respectively, as well as a mutation in a GDSL-like esterase/lipase gene altering the levels of dicaffeoyl-quinic acids. These findings provide a cornerstone for pangenome-assisted breeding, enabling detailed analyses of genetic diversity, domestication history, and trait evolution in eggplant.Eggplants are important vegetables worldwide. Here, the authors report 40 genome assemblies of Solanum melongena, its progenitor S. insanum and the allied species S. incanum to construct two pangenomes, and identify loci associated with multiple traits via pangenome-wide association analysis.
ISSN:	2041-1723
DOI:	10.1038/s41467-025-64866-1
Джерело:	Health & Medical Collection