Repurposing FDA-Approved Drugs as Hendra Virus RNA-Dependent RNA Polymerase Inhibitors: A Comprehensive Computational Drug Discovery Approach

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Pubblicato in:	Viruses vol. 17, no. 12 (2025), p. 1613-1633
Autore principale:	Lalu, Anjana C
Altri autori:	Kundil, Varun Thachan, Joseph Bristow Ben, Dev Radul R., Amritha, Thaikkad, Subair Suhail, Raju Rajesh, Abhithaj, Jayanandan
Pubblicazione:	MDPI AG
Soggetti:	Food & Drug Administration > FDA Australia Physiology RNA polymerase RNA-directed RNA polymerase Toxicity Binding sites Hydrogen Drug development Computer applications DNA-directed RNA polymerase Antiviral agents Bioavailability Proteins Crystal structure Simulation Fatalities RNA viruses Pharmacokinetics FDA approval Pamidronic acid Conserved sequence Bisphosphonates Ligands Viruses Homology
Accesso online:	Citation/Abstract Full Text + Graphics Full Text - PDF
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