The impact of human papillomavirus positivity and genotype on sexual dysfunction and psychosexual stress

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Yayımlandı:Turkish Journal of Obstetrics and Gynecology vol. 22, no. 4 (Dec 2025), p. 287-292
Yazar: Karadağ, Ceyda
Diğer Yazarlar: Saniye Merve Gül Kara, Gazi Güner, Dağdeviren, Emrah, Pota, Ali, Tercan, Ergün, İnal, Mehmet Murat
Baskı/Yayın Bilgisi:
Galenos Publishing House
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022 |a 2149-9322 
022 |a 2149-9330 
022 |a 1307-699X 
024 7 |a 10.4274/tjod.galenos.2025.88949  |2 doi 
035 |a 3287380586 
045 2 |b d20251201  |b d20251231 
100 1 |a Karadağ, Ceyda 
245 1 |a The impact of human papillomavirus positivity and genotype on sexual dysfunction and psychosexual stress 
260 |b Galenos Publishing House  |c Dec 2025 
513 |a Journal Article 
520 3 |a ObjectiveThis study aimed to investigate the relationship between human papillomavirus (HPV) positivity, genotype, and female sexual dysfunction, particularly anorgasmia and psychosexual stress, among women participating in a cervical cancer screening program. It also examined whether HPV infection or genotype independently contributes to sexual dysfunction after adjusting for sociodemographic and reproductive factors.Materials and MethodsThis prospective, cross-sectional study included 1,353 sexually active women aged 25-65 years who underwent HPV testing at Antalya City Hospital between May and September 2025. Participants completed validated questionnaires including the Female Sexual Function Index, Arizona Sexual Experiences Scale, Beck Depression Inventory, and Beck Anxiety Inventory. Sociodemographic, reproductive, and clinical characteristics were recorded, and HPV genotyping was performed using polymerase chain reaction-based assays.ResultsAnorgasmia was identified in 31.5% of participants (n=427). It was significantly more common among unemployed women (84.1% vs. 71.6%; odds ratio =2.09, 95% confidence interval: 1.56-2.82; p=0.0001). Higher gravidity, parity, number of living children, and elevated vaginal pH were all associated with anorgasmia (p<0.05). No significant association was found between HPV positivity or genotype and anorgasmia (p>0.05).ConclusionAnorgasmia is primarily influenced by sociodemographic and reproductive factors, such as occupation, education level, parity, and vaginal environment, rather than HPV infection or genotype. These findings emphasize the importance of biopsychosocial and culturally sensitive approaches in evaluating and managing women’s sexual health. 
653 |a Infections 
653 |a Womens health 
653 |a Sexual intercourse 
653 |a Anxiety 
653 |a Sexual disorders 
653 |a Stress 
653 |a Vagina 
653 |a Gynecology 
653 |a Parity 
653 |a Sociodemographics 
653 |a Questionnaires 
653 |a Cervical cancer 
653 |a Females 
653 |a Educational attainment 
653 |a Genotype & phenotype 
653 |a Human papillomavirus 
653 |a Medical screening 
653 |a Education 
700 1 |a Saniye Merve Gül Kara 
700 1 |a Gazi Güner 
700 1 |a Dağdeviren, Emrah 
700 1 |a Pota, Ali 
700 1 |a Tercan, Ergün 
700 1 |a İnal, Mehmet Murat 
773 0 |t Turkish Journal of Obstetrics and Gynecology  |g vol. 22, no. 4 (Dec 2025), p. 287-292 
786 0 |d ProQuest  |t Health & Medical Collection 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3287380586/abstract/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text  |u https://www.proquest.com/docview/3287380586/fulltext/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3287380586/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch