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Innovative Regenerative Treatment with Nanofat Injection for Hypertensive Ischemic Leg Ulcer: A Case Report

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Xuất bản năm:Case Reports in Dermatology vol. 17, no. 1 (Jan-Dec 2025), p. 342
Tác giả chính: Terrasa, Mélodie
Tác giả khác: Majzoub, Marwa, Jeudy, Geraldine, Moris, Vivien
Được phát hành:
S. Karger AG
Những chủ đề:
Leg ulcers
Liposuction
Quality of life
Plastic surgery
Wound healing
Adipocytes
Hypertension
Body fat
Pain
Females
Ischemia
Skin & tissue grafts
Local anesthesia
Patient satisfaction
Narcotics
Analgesics
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Bài tóm tắt:Introduction Chronic wounds affect millions worldwide, leading to significant morbidity and reduced quality of life [1]. The patient reported severe pain with a VAS = 8/10 (Visual Analog Scale) and mobility restrictions, significantly impairing her quality of life. The procedure began with an infiltration of 100 cm3 of 0.9% NaCl diluted with a solution containing 1% lidocaine hydrochloride (10 mg/mL) and adrenaline (0.005 mg/mL) at the donor site (periumbilical region). The treatment not only resulted in the complete healing of a chronic wound persisting for over 5 years, despite previous skin graft failures, but also significantly reduced pain and improved the patient’s quality of life. In this case, the pain was severe, with a VAS of 8/10, associated with mobility restrictions and a significant impairment of her quality of life.
số ISSN:1662-6567
Nguồn:Health & Medical Collection