Biopharmaceutics modeling and simulations : theory, practice, methods, and applications /

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書目詳細資料
主要作者: Sugano, Kiyohiko
格式: 電子 電子書
語言:英语
出版: Hoboken, N.J. : Wiley, [2012]
主題:
在線閱讀:https://biblioteca.ues.edu.sv/acceso/elibro/?url=https%3A%2F%2Felibro.net%2Fereader%2Fbiblioues/183746
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書本目錄:
  • Introduction
  • Theoretical framework I : solubility
  • Theoretical framework II : dissolution
  • Theoretical framework III : biological membrane permeation
  • Theoretical framework IV : gastrointestinal transit models and integration
  • Physiology of gastrointestinal tract and other administration sites in humans and animals
  • Drug parameters
  • Validation of mechanistic models
  • Bioequivalence and biopharmaceutical classification system
  • Dose and particle size dependency
  • Enabling formulations
  • Food effect
  • Biopharmaceutical modeling for miscellaneous cases
  • Intestinal transporters
  • Strategy in drug discovery and development
  • Epistemology of biopharmaceutical modeling and good simulation practice.