Azala

Applicability of the CANTAB-PAL Computerized Memory Test in Identifying Amnestic Mild Cognitive Impairment and Alzheimer's Disease

Gorde:
Argitaratua izan da:Dementia and Geriatric Cognitive Disorders vol. 34, no. 2 (Sep 2012), p. 83-89
Egile nagusia: Junkkila, Jenny
Beste egile batzuk: Oja, Sakari, Laine, Matti, Karrasch, Mira
Argitaratua:
S. Karger AG
Gaiak:
Aged
Aged, 80 & over
Alzheimer Disease > diagnosis
Case-Control Studies
Discriminant Analysis
Female
Humans
Male
Middle Aged
Mild Cognitive Impairment > diagnosis
Neuropsychological Tests
Paired-Associate Learning
Aging
Recall
Delayed
Cognitive impairment
Learning
Delayed recall
Errors
Word lists
Memory
Educational activities
Medical screening
Computerization
Tests
Alzheimer's disease
Paired associate learning
Sarrera elektronikoa:Citation/Abstract
Full Text - PDF
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
Laburpena:Aim: To compare the diagnostic accuracy of a computerized test, the CANTAB paired associate learning (PAL) to that of an established and validated noncomputerized test, the CERAD Wordlist Learning task in differentiating between normal aging, aMCI and AD in a cross-sectional design. Methods: 58 participants were assessed (19 with mild probable AD, 17 aMCI, 22 healthy controls). Results: The variables found to best discriminate between the three groups were the CANTAB PAL total errors adjusted (p < 0.0001, 81.0% of the cases correctly classified), and CERAD Wordlist Learning Delayed Recall (p < 0.0001, 77.6% of the cases correctly classified). Using both PAL total errors adjusted and Wordlist Learning Delayed Recall, 84.5% of the cases were correctly classified. Discussion: The results suggest that the CANTAB could be used for screening of AD-typical memory impairment. Copyright © 2012 S. Karger AG, Basel [PUBLICATION ABSTRACT]   To compare the diagnostic accuracy of a computerized test, the CANTAB paired associate learning (PAL) to that of an established and validated noncomputerized test, the CERAD Wordlist Learning task in differentiating between normal aging, aMCI and AD in a cross-sectional design. 58 participants were assessed (19 with mild probable AD, 17 aMCI, 22 healthy controls). The variables found to best discriminate between the three groups were the CANTAB PAL total errors adjusted (p < 0.0001, 81.0% of the cases correctly classified), and CERAD Wordlist Learning Delayed Recall (p < 0.0001, 77.6% of the cases correctly classified). Using both PAL total errors adjusted and Wordlist Learning Delayed Recall, 84.5% of the cases were correctly classified. The results suggest that the CANTAB could be used for screening of AD-typical memory impairment.
ISSN:1420-8008
1421-9824
1013-7424
DOI:10.1159/000342116
Baliabidea:Science Database