Phylogenetic methods come of age: Testing hypotheses in an evolutionary context

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Pubblicato in:	Science vol. 276, no. 5310 (Apr 11, 1997), p. 227-232
Autore principale:	Huelsenbeck, John P
Altri autori:	Rannala, Bruce
Pubblicazione:	The American Association for the Advancement of Science
Soggetti:	Evolution Evolution, Molecular Phylogeny Molecules Simulation Biology Biologists Parasites Deoxyribonucleic acid > DNA Computer Simulation Mathematical Models Communicable Diseases Probability Topology Hypothesis Testing Monte Carlo Methods Maximum Likelihood Statistics Environmental
Accesso online:	Citation/Abstract Full Text + Graphics Full Text - PDF
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Descrizione
Abstract:	The use of molecular phylogenies to examine evolutionary questions has become commonplace with the automation of DNA sequencing and the availability of efficient computer programs to perform phylogenetic analyses. The application of computer simulation and likelihood ratio tests to evolutionary hypotheses represents a recent methodological development in this field. Likelihood ratio tests have enabled biologists to address many questions in evolutionary biology that have been difficult to resolve in the past, such as whether host-parasite systems are cospeciating and whether models of DNA substitution adequately explain observed sequences.
ISSN:	0036-8075 1095-9203
Fonte:	Science Database