Phylogenetic methods come of age: Testing hypotheses in an evolutionary context

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Detalles Bibliográficos
Publicado en:	Science vol. 276, no. 5310 (Apr 11, 1997), p. 227-232
Autor Principal:	Huelsenbeck, John P
Outros autores:	Rannala, Bruce
Publicado:	The American Association for the Advancement of Science
Materias:	Evolution Evolution, Molecular Phylogeny Molecules Simulation Biology Biologists Parasites Deoxyribonucleic acid > DNA Computer Simulation Mathematical Models Communicable Diseases Probability Topology Hypothesis Testing Monte Carlo Methods Maximum Likelihood Statistics Environmental
Acceso en liña:	Citation/Abstract Full Text + Graphics Full Text - PDF
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Descripción
Resumo:	The use of molecular phylogenies to examine evolutionary questions has become commonplace with the automation of DNA sequencing and the availability of efficient computer programs to perform phylogenetic analyses. The application of computer simulation and likelihood ratio tests to evolutionary hypotheses represents a recent methodological development in this field. Likelihood ratio tests have enabled biologists to address many questions in evolutionary biology that have been difficult to resolve in the past, such as whether host-parasite systems are cospeciating and whether models of DNA substitution adequately explain observed sequences.
ISSN:	0036-8075 1095-9203
Fonte:	Science Database