Effects of Transcranial Pulse Stimulation of the Primary Motor Cortex on Motor Performance in Healthy Adults: A Randomized Crossover Pilot Study
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| Pubblicato in: | CNS Neuroscience & Therapeutics vol. 31, no. 12 (Dec 1, 2025) |
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| Autore principale: | |
| Altri autori: | , , , , , , , , , |
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John Wiley & Sons, Inc.
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| Accesso online: | Citation/Abstract Full Text Full Text - PDF |
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| 022 | |a 1755-5930 | ||
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| 024 | 7 | |a 10.1002/cns.70711 |2 doi | |
| 035 | |a 3284941604 | ||
| 045 | 0 | |b d20251201 | |
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| 100 | 1 | |a Qin, Penny Ping |u Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China | |
| 245 | 1 | |a Effects of Transcranial Pulse Stimulation of the Primary Motor Cortex on Motor Performance in Healthy Adults: A Randomized Crossover Pilot Study | |
| 260 | |b John Wiley & Sons, Inc. |c Dec 1, 2025 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a ABSTRACT Aims We aimed to investigate the behavioral aftereffects of a novel noninvasive brain stimulation technique—transcranial pulse stimulation (TPS)—applied over the right motor cortex (rM1) in healthy adults. Methods Thirty‐four healthy adults underwent a randomized, subject‐ and analyst‐ blind, crossover trial, receiving active TPS over the rM1 or control TPS over the vertex in two sessions 24 h apart. Motor performance was assessed using the Nine‐Hole Peg Test (NHPT) and the Simple Reaction Time Task (SRTT) before, immediately after, and every 10 min for 40 min after each session. A linear mixed model and post hoc analyses were applied to evaluate the effects. Results No significant interaction effect (stimulation condition × time) was found. The left‐hand NHPT performance significantly improved from 10 min post‐TPS onward in both conditions (ps ≤ 0.002). Conclusion A single session of rM1‐TPS does not yield significant improvements in motor dexterity compared to vertex‐TPS. Future well‐powered studies with a sham control condition and multiple stimulation sessions are needed to investigate the aftereffects using a combination of neurophysiological and neuroimaging approaches. Trial Registration This study was registered in ClinicalTrial.gov in April 2024 (NCT06312930) | |
| 610 | 4 | |a Hong Kong Polytechnic University | |
| 651 | 4 | |a China | |
| 651 | 4 | |a Hong Kong China | |
| 653 | |a Lithotripsy | ||
| 653 | |a Pilot projects | ||
| 653 | |a Brain research | ||
| 653 | |a Blindness | ||
| 653 | |a Mental disorders | ||
| 653 | |a Cortex (motor) | ||
| 653 | |a Reaction time task | ||
| 653 | |a Neuroimaging | ||
| 653 | |a Motor task performance | ||
| 653 | |a Ultrasonic imaging | ||
| 653 | |a Parkinson's disease | ||
| 700 | 1 | |a Chak, Ivan Kin‐Yeung |u Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China | |
| 700 | 1 | |a Kan, Rebecca Lai‐Di |u Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China | |
| 700 | 1 | |a Jin, Min‐Xia |u Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China | |
| 700 | 1 | |a Zhang, Bella Bing‐Bing |u Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China | |
| 700 | 1 | |a Xia, Adam Wei‐Li |u Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China | |
| 700 | 1 | |a Lin, Tim Tian‐Ze |u Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China | |
| 700 | 1 | |a Wang, Sharie Xiao |u Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China | |
| 700 | 1 | |a Liu, Jian‐Hui |u Department of Anesthesiology, School of Medicine, Tongji University, Shanghai, China | |
| 700 | 1 | |a Cheung, Teris |u School of Nursing, The Hong Kong Polytechnic University, Hong Kong, China | |
| 700 | 1 | |a Kranz, Georg S. |u Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China | |
| 773 | 0 | |t CNS Neuroscience & Therapeutics |g vol. 31, no. 12 (Dec 1, 2025) | |
| 786 | 0 | |d ProQuest |t Health & Medical Collection | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/3284941604/abstract/embedded/L8HZQI7Z43R0LA5T?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text |u https://www.proquest.com/docview/3284941604/fulltext/embedded/L8HZQI7Z43R0LA5T?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/3284941604/fulltextPDF/embedded/L8HZQI7Z43R0LA5T?source=fedsrch |