(Unlearned) lessons from John Graunt and Kenneth Rothman: A "CLASSic" example

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書誌詳細
出版年:	Clinical Therapeutics vol. 25, no. 11 (Nov 2003), p. 2891
第一著者:	Arellano, Felix M.
団体著者:	Class
その他の著者:	Castellsague, Jordi
出版事項:	Elsevier Limited
主題:	Anti-Inflammatory Agents, Non-Steroidal > adverse effects Data Interpretation, Statistical Endpoint Determination Epidemiologic Methods Epidemiologic Research Design Humans Peptic Ulcer > chemically induced Randomized Controlled Trials as Topic
オンライン･アクセス:	Citation/Abstract Full Text Full Text - PDF
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その他の書誌記述
抄録:	This commentary reviews the work of John Graunt and Kenneth J. Rothman on statistical significance and the need for prespecification of study end points. The authors argue that it is dangerous to substitute oversimplifications based exclusively on whether a result has reached statistical significance for a rational process of causal inference. An example is given based on the Celecoxib Lonngterm Arthritis Safety Study. This commentary reviews the work of John Graunt and Kenneth J. Rothman on statistical significance and the need for prespecification of study end points. The authors argue that it is dangerous to substitute oversimplifications based exclusively on whether a result has reached statistical significance for a rational process of causal inference. An example is given based on the Celecoxib Long-term Arthritis Safety Study.
ISSN:	0149-2918 1879-114X
DOI:	10.1016/S0149-2918(03)80341-7
ソース:	Healthcare Administration Database